EBPS EBPS

EBPS Biennial Meeting 2021

EBPS Biennial Meeting 2021

EBPS Biennial Meeting 2021

Online • 13-16 July 2021

Onlines
13-16 July 2021

Online
13-16 July 2021

Preliminary Programme

 
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  • 14:00-14:15

    Opening

    14:15-14:30

    Instructions on meeting portal

    14:30-14:45

    Online Meet & Greet

    14:45-15:15

    Opening Plenary Session

    Lecture 1

    David Nutt (London, United Kingdom)

    Resurrecting psychedelic medicine through brain science

    15:20-16:40

    Parallel Sessions

    Symposium 1: Neurocircuitry of traumatic stress and aversive learning; lessons learned from neuronal recordings to circuit manipulation
    Chair: Rachel Moloney (Cork, Ireland)

    Anna Beyeler (Bordeaux, France)

    Role of divergent projection neurons of the insular cortex in anxiety- and valence-related behaviors

    Tom Kash (Chapel Hill, NC, USA)

    Probing modulatory dynamics in the extended amygdala during aversive learning

    Stephen Maren (College Station, TX, USA)

    Neural circuits for stress-induced impairments in fear extinction

    Rachel Moloney (Cork, Ireland)

    Traumatic stress-induced changes in contextual fear learning; role of cortico-limbic circuitry

    Symposium 2: New developments in alcohol use disorder research and drug development
    Chair: Andrew Lawrence (Parkville, Australia)

    Cody Siciliano (Nashville, TN, USA)

    Kappa-opioid receptor regulation of reinforcement learning

    Andrew Lawrence (Parkville, Australia)

    Muscarinic acetylcholine receptors in alcohol use disorder

    Estelle Barbier (Linköping, Sweden)

    Synaptotagmin1 and alcohol-associated behaviors

    Leigh Walker (Melbourne, Australia)

    Sex differences in binge drinking: The role of cocaine and amphetamine regulated transcript (CART)

    Symposium 3: The endocannabinoid system, neurodevelopment and autism
    Chair: Michelle Roche (Galway, Ireland)

    Michelle Roche (Galway, Ireland)

    Endocannabinoid and opioid modulation of autistic-like behaviour in a the valproic acid model

    Antonia Manduca (Rome, Italy)

    Role of the endocannabinoid system in genetic and environmental preclinical models of ASD

    Erica Zamberletti (Varese, Italy)

    Cannabidivarin modulation of ASD-like signs in the prenatal valproic acid rat model of autism: behavioural and neurochemical studies

    Eva  Marco (Madrid, Spain)

    The endocannabinoid system in the consequences of early life stress

    16:45-18:05

    Parallel Sessions

    Symposium 4: Stress effects on neural coding of threat across timescales
    Chair: Alfred Kaye (New Haven, CT, USA)

    Wei-li Chang (New York, NY, USA)

    Early life stress effects on fear-related ventral hippocampal activity

    Alfred Kaye (New Haven, CT, USA)

    Prefrontal acetylcholine and norepinephrine structure arousal after traumatic stress

    Cornelius Gross (Rome, Italy)

    Territory cells in the mammalian hypothalamus

    Bianca Ambrogina Silva (Lausanne, Switzerland)

    Brain circuits of fear attenuation

    Symposium 5: Alternative strategies for drug addiction treatment
    Chairs: Silvana De Pirro (Linköping, Sweden) & Marco Venniro (Baltimore, MD, USA)

    Ingrid Reverte (Rome, Italy)

    Effect of social choice-induced voluntary abstinence on incubation of methamphetamine craving and AMPA receptor expression in the nucleus accumbens core

    Laurence Hunt (Oxford, United Kingdom)

    Towards fast, robust single-subject neural markers of decision making for computational psychiatry

    Guru Løseth (Oslo, Norway)

    Social support, stress relief and opioids: Do the stress-relieving effects of social support depend on opioid-mediated mechanisms?

    Margaret Haney (New York, NY, USA)

    Human Laboratory Models of Drug Self-administration: Drug vs Money

    Symposium 6: Neurobiological correlates and pharmacotherapeutic implications of the glucagon-like peptide-1 (GLP-1) system: An emerging target in neuropsychiatry
    Chair: Mehdi Farokhnia (Baltimore, MD, USA)

    Sriparna Ghosal (Lausanne, Switzerland)

    The role of central glucagon-like peptide-1 (GLP-1) in stress regulation

    Mehdi Farokhnia (Baltimore, MD, USA)

    Glucagon-like peptide-1 (GLP-1) system is modulated by acute and chronic exposure to alcohol: findings from human laboratory experiments and a brain postmortem study.

    Rodrigo  Mansur (Toronto, Canada)

    Glucagon-like peptide-1 receptor (GLP-1R) agonists as potential treatments for cognitive dysfunction in mood disorders

    Elizabeth Rhea (Seattle, WA, USA)

    Blood-brain barrier transport of glucagon-like peptide-1 receptor (GLP-1R) agonists

    18:05-18:45

    Break / Meet / Discuss

    18:45-19:45

    Poster Session

    20:00-20:30

    Plenary Session

    Lecture 2

    Eveline Crone (Leiden, Netherlands)

    Adolescent brain development: A window of opportunity for social-affective engagement

    20:30-21:00

    Lecture chat

  • 14:00-14:30

    Plenary Session

    Lecture 3

    Joshua Buckholtz (Cambridge, MA, USA)

    Cognitive and neurobiological mechanisms for self-control failure in psychiatric illness

    14:35-15:55

    Parallel Sessions

    Symposium 7: Determining the role of habit in substance use disorders
    Chair: Youna Vandaele (Prilly, Switzerland)

    Christina Gremel (San Diego, CA, USA)

    Alcohol dependence biasing habits? Loss of outcome devaluation and enhanced contingency control

    Stephanie Groman (Minneapolis, MN, USA)

    Model-free and model-based learning is disrupted following methamphetamine self-administration in rats

    Youna Vandaele (Prilly, Switzerland)

    Habitual preference for a nondrug reward in a drug choice setting

    Lee Hogarth (Exeter, United Kingdom)

    Habit and compulsion theories of addiction based on animal models have not translated successfully to humans

    Symposium 8: Computational neuroethology
    Chair: Sandeep Datta (Boston, MA, USA)

    Mackenzie Mathis (Lausanne, Switzerland)

    The DeepLabCut ModelZoo: towards plug-in-play solutions for tracking animals in ethological contexts

    Fatih Mehmet Yanik (Zurich, Switzerland)

    Deep-learning based identification, and end-to-end behavior classification for interacting primates and mice in complex environments

    Christopher Harvey (Boston, MA, USA)

    Machine learning pipelines for supervised behavior classification from raw video pixels

    Ami Citri (Jerusalem, Israel)

    Automated behavioral annotation unveils the role of the ventro-lateral striatum in cocaine-induced stereotypies

    Symposium 9: Susceptibility to false memories following cannabis and MDMA: clinical and forensic implications
    Chairs: Lilian Kloft (Maastricht, Netherlands) & Jan Ramaekers (Maastricht, Netherlands)

    Lilian Kloft (Maastricht, Netherlands)

    Sensitivity to false memories during cannabis and MDMA intoxication: forensic implications

    Manoj Doss (Baltimore, MD, USA)

    Shared and unique effects of THC and MDMA on emotional memory, memory distortion, and subprocesses of episodic memory

    Rachel Lees (Bath, United Kingdom)

    Effect of 4-week cannabidiol treatment on memory and cognition in a clinical trial for cannabis use disorder

    Sagnik Bhattacharyya (London, United Kingdom)

    Associations between cannabis use, memory deficits and psychosis

    15:55-16:10

    Break / Meet / Discuss

    16:10-17:30

    Parallel Sessions

    Symposium 10: The pharmacokinetic determinants of substance use disorder
    Chair: Daniele Caprioli (Rome, Italy)

    Daniele Caprioli (Rome, Italy)

    The impact of continuously high versus intermittently high brain levels of heroin on incubation of craving

    Susan Ferguson (Seattle, WA, USA)

    Intermittent but not continuous access to illicit drugs produces individual variability in addiction susceptibility in rats

    David Epstein (Baltimore, MD, USA)

    The clinical relevance of temporal patterns of drug administration, onset of effects, and offset of effects

    Florence Allain (Montreal, Canada)

    Amphetamine maintenance therapy during intermittent cocaine self-administration in rats attenuates psychomotor and dopamine sensitization and reduces addiction-like behavior

    Symposium 11: VTA glutamatergic neurons: often ignored but key players in the fields of innate behavior and psychopathology
    Chairs: Marisela Morales (Baltimore, MD, USA) & Flavia Barbano (Baltimore, MD, USA)

    William Wisden (London, United Kingdom)

    The role of VTA glutamatergic neurons in sleep modulation

    Flavia Barbano (Baltimore, MD, USA)

    VTA glutamatergic neurons mediate innate defensive behavior

    Ryan Drenan (Winston-Salem, NC, USA)

    Nicotinic cholinergic modulation of VTA glutamate neurons

    Matthew Anderson (Boston, MA, USA)

    Sociability driving glutamate neurons in the ventral tegmental area: a convergent target of autism genetics and seizure effects

    Symposium 12: An emerging role for neurofunctional domain approaches in modern CNS drug discovery
    Chair: Rudy Schreiber (Maastricht, Netherlands)

    Sarah Morris with Bill Potter and Bruce Cuthbert (Bethesda, MD, USA)

    A paradigm shift from DSM-5 to research domain criteria: application to translational CNS drug development

    Laura Kwako with George Koob (Bethesda, MD, USA)

    Application of neurofunctional domains in the development of novel therapeutics to treat SUD

    Ulrike Schmidt (Bonn, Germany) with Eric Vermetten (Leiden, Netherlands)

    Integration of research domain criteria into post-praumatic psychopathology

    Jaymin Upadhyay (Boston, MA, USA) with Rudy Schreiber (Maastricht, Netherlands)

    Conceptual analyses using a dimensional framework of the OUD-PTSD comorbidsState: implications for novel therapies

    17:35-18:05

    Plenary Session

    Lecture 4

    Marina Picciotto (New Haven, CT, USA)

    Acetylcholine signaling in the basolateral amygdala during reward learning

    18:05-18:40

    Break / Meet / Discuss

    18:40-19:40

    Poster Session

  • 13:15-13:45

    Plenary Session

    Young Scientist Award

    Leah Mayo (Linköping, Sweden)

    (Not) lost in translation: the endocannabinoid system as a novel target for stress-related disorders

    13:45-14:30

    Plenary Session

    Distinguished Achievement Award

    Aldo Badiani (Rome, Italy)

    Neuropharmacology of addictive drugs: Beyond pharmacodynamics and pharmacokinetics

    14:35-15:55

    Parallel Sessions

    Symposium 13: Emotions in alcohol use and misuse – evidence from behavioural, eye tracking, and neuroimaging research
    Chairs: Theodora Duka (Brighton, United Kingdom) & Aleksandra Herman (Warsaw, Poland)

    Séverine Lannoy (Richmond, VA, USA)

    Emotional disturbances in binge alcohol drinking

    Aleksandra Herman (Warsaw, Poland)

    Alexithymia and valence bias in alcohol binge drinking

    Arthur Pabst (Louvain, Belgium)

    Emotion recognition and beyond: toward an expansion of social cognition studies in severe alcohol use disorder (SAUD)

    Kyriaki Nikolaou (Brighton, United Kingdom)

    Emotional (dys)regulation in alcohol use disorder

    Symposium 14: Propagating motivatinal value across the memory network
    Chair: Mihaela Iordanova (Montreal, Canada)

    Mihaela Iordanova (Montreal, Canada)

    Differential dependence of secondary fear triggers on the original fear memory

    Nathan Holmes (Sydney, Australia)

    Connectivity between the perirhinal cortex and the basolateral amygdala regulate sensory preconditioning

    Evan Hart (Baltimore, MD, USA)

    Anterior cingulate neurons encode sensory associative information during sensory preconditioning

    Arnau Busquets-Garcia (Barcelona, Spain)

    Role of the hippocampus in sensory preconditioning

    Symposium 15: Compulsivity and neurobehavioural plasticity
    Chairs: Margarita Moreno (Almeria, Spain) & Trevor Robbins (Cambridge, United Kingdom)

    Tobias Hauser (London, United Kingdom)

    Neural basis of compulsive behaviour in the developing adolescent human brain

    Aude Belin-Rauscent (Cambridge, United Kingdom)

    Neural system basis of compulsive cocaine-seeking in rats using MRI

    Margarita Moreno (Almeria, Spain)

    Neurobehavioural basis of compulsive drinking in rats and its treatment

    Martijn Figee (New York, NY, USA)

    Treatment of OCD with deep brain stimulation

    15:55-16:10

    Break / Meet / Discuss

    16:10-17:30

    Parallel Sessions

    Symposium 16: Corticostriatal mechanisms of inhibitory control: a tribute to Dawn Eagle
    Chair: Amy Milton (Cambridge, United Kingdom)

    Trevor Robbins (Cambridge, United Kingdom)

    Fractionating impulsivity: neural and psychiatric implications

    Christelle Baunez (Marseille, France)

    The subthalamic nucleus in the circuit of inhibition control

    Emma Robinson (Bristol, United Kingdom)

    Investigating noradrenergic mechanisms and impulse control using translational animal models

    Karly Turner (Sydney, Australia)

    Are impulsive actions habitual?

    Symposium 17: The role of the gut microbiome in drug addiction
    Chair: John Cryan (Cork, Ireland)

    Rubén García-Cabrerizo (Cork, Ireland)

    Microbiota-gut-brain axis as a regulator of reward and social processes: relevance to cocaine addiction

    Nathalie Delzenne (Louvain, Belgium)

    Gut microbiota on food and alcohol addiction

    Drew Kiraly (New York, NY, USA)

    Gut microbial metabolites play a critical role in opioid seeking and nucleus accumbens transcriptional control

    Sabita Roy (Miami, FL, USA)

    Gut microbiome brain axis in morphine tolerance

    Symposium 18: Behavioral and molecular factors in cocaine reinforcement, choice, and reward
    Chair: William Stoops (Lexington, KY, USA)

    Erin Calipari (Nashville, TN, USA)

    Divergent molecular adaptations in the nucleus accumbens control cocaine reinforcement in males and females

    Serge Ahmed (Bordeaux, France)

    The history and significance of animal research on drug choice

    William Stoops (Lexington, KY, USA)

    Pharmacological manipulation of cocaine choice in humans

    Karen Ersche (Cambridge, United Kingdom)

    I know it is bad, but I’ll do it again.

    17:35-18:05

    Nanopresentations

    18:05-18:40

    Break / Meet / Discuss

    18:40-19:40

    Poster Session

  • 14:00-15:20

    Parallel Sessions

    Symposium 19: Many faces of stress: different approaches to understand a complex phenomenon
    Chair: Plinio Casarotto (Helsinki, Finland)

    Carmen Sandi (Lausanne, Switzerland)

    The power of behaviour to reveal vulnerability to stress-related disorders and underlying neural mechanisms

    Sabine Spijker (Amsterdam, Netherlands)

    Incubation of depression

    Caroline Biojone (Helsinki, Finland)

    Modulation of TRKB by nitric oxide: from cellular mechanisms to behavior

    Maurizio Popoli (Milan, Italy)

    Stressed synapses, pathophysiology of mental illness and glutamate-based therapeutic approach

    Symposium 20: Getting under the hood: Identifying the scope of dopamine’s role in learning (and behavior)
    Chair: Geoffrey Schoenbaum (Baltimore, MD, USA)

    Geoffrey Schoenbaum (Baltimore, MD, USA)

    Identity prediction errors in the rat dopamine neurons and their role in stimulus-outcome learning

    Thorsten Kahnt (Chicago, IL, USA)

    Identity prediction errors in the human midbrain and their role in stimulus-outcome learning

    Ingo Willuhn (Amsterdam, Netherlands)

    Regional specialization of dopamine transients in the rat striatum during appetitive and aversive stimulus-outcome learning

    Roshan Cools (Nijmegen, Netherlands)

    Striatal dopamine-dependent effects of dopamine drugs on human stimulus-outcome learning

    15:20-15:40

    Awards Ceremony

    15:40-16:05

    Break / Meet / Discuss

    16:05-17:25

    Parallel Sessions

    Symposium 21: The secret of the magic potion: Cognitive enhancement using pharmacology
    Chair: Anke Sambeth (Maastricht, Netherlands)

    Carl Roberts (Liverpool, United Kingdom)

    How effective are pharmaceuticals for cognitive enhancement in healthy adults? A series of meta-analyses of cognitive performance during acute administration of modafinil, methylphenidate and D-amphetamine

    Anke Sambeth (Maastricht, Netherlands)

    Intellectual doping with cognition enhancing drugs

    Dorothee Horstkötter (Maastricht, Netherlands)

    Cognitive Enhancement: the ethical debate

    Symposium 22: Drug harms and drug policy
    Chair: Jan Ramaekers (Maastricht, Netherlands)

    David Nutt (London, United Kingdom)

    On ranking of drug harms

    Wim van den Brink (Amsterdam, Netherlands)

    Developing a new national MDMA policy: Results of a multidecision multi-criterion decision analysis (MD-MCDA)

    Jurgen Rehm (Toronto, Canada)

    Changing policies on recreational and medical use of cannabis

    Jan Ramaekers (Maastricht, Netherlands)

    Policy and research on novel psychoactive substances

    Symposium 23: Do not lose it in the crowd. Novel statistical methods and machine learning techniques in assessing inter-individual variability in behavioral neuroscience
    Chair: Kshitij Jadhav (Prilly, Switzerland)

    Maxime Fouyssac (Cambridge, United Kingdom)

    From heterogeneity to homogenous trends in individual trajectories: experimental and statistical approaches to study inter-individual differences in the vulnerability to addiction

    Kshitij Jadhav (Prilly, Switzerland)

    Combining supervised and unsupervised machine learning models to identify rats at higher risk of alcohol or cocaine use disorder

    Brice Bathellier (Paris, France)

    Capturing learning dynamics and interindividual variability in mice performing a sound discrimination task

    Patricia Lockwood (Birmingham, United Kingdom)

    A reinforcement learning approach to understanding prosocial behaviour

    17:25-17:55

    Closing Ceremony